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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, Yorvit | CF | San Cristobal de las Casas Possums | 28 | 04/29/2041 | Panama | PAN | Right | Right | 5' 9" | 180 lbs | - |
| Salgardo, Gabriel | SS | Churuquita Grande Blackbirds | 25 | 08/01/2044 | Santo Domingo | DOM | Right | Right | 5' 9" | 175 lbs | - |
| Sampson, Aldwyn | CF | El Puerto Anchoas | 23 | 03/20/2047 | Juanacatlan | MEX | Right | Right | 5' 10" | 175 lbs | - |
| Sánchez, Carlos | 2B | Tangping Zephyrs | 31 | 11/21/2038 | Ojocaliente | MEX | Switch | Right | 5' 11" | 195 lbs | - |
| Sánchez, Gervasio | 2B | Tangping Zephyrs | 26 | 12/28/2043 | Santiago de Cuba | CUB | Right | Right | 6' 1" | 205 lbs | - |
| Santillanes, Kent | RP | Los Reyes Punishers | 34 | 06/03/2035 | Mexico City | MEX | Right | Right | 6' 5" | 215 lbs | - |
| Santos, Colón | RP | Donnacona Toads | 21 | 05/09/2048 | Cativa | PAN | Right | Right | 6' 2" | 185 lbs | - |
| Sanudo, Manuel | SS | Ciudad Valles Screamers | 26 | 07/07/2043 | San Pedro de Macorís | DOM | Right | Right | 6' 0" | 190 lbs | - |
| Sasaki, Yoshiaga | RP | Churuquita Grande Blackbirds | 25 | 07/01/2044 | Yokohama | JPN | Right | Right | 6' 3" | 200 lbs | - |
| Saunas, Antón | C | El Puerto Anchoas | 29 | 02/07/2041 | Lilburn | USA | Left | Right | 6' 1" | 200 lbs | - |
| Serrana, Raúl | RP | Los Reyes Punishers | 32 | 01/23/2038 | Guaynabo | PUR | Right | Right | 6' 2" | 200 lbs | - |
| Severra, Fabián | 3B | San Cristobal de las Casas Possums | 26 | 12/23/2043 | Valencia | VEN | Switch | Right | 6' 4" | 195 lbs | - |
| Solares, Vicente | CF | San Cristobal de las Casas Possums | 23 | 05/13/2046 | Guaynabo | PUR | Left | Right | 5' 11" | 180 lbs | - |
| Sop, Sang-hwa | SP | Free Agent | 26 | 06/06/2043 | Kwangmyong | KOR | Right | Right | 6' 0" | 190 lbs | - |
| Stendall, Seldon | SP | Tangping Zephyrs | 23 | 07/30/2046 | Farmington | USA | Right | Right | 6' 3" | 195 lbs | - |
| Stoddart, John | 3B | Free Agent | 29 | 03/20/2041 | Quebec | CAN | Right | Right | 6' 0" | 190 lbs | - |
| Sun, Hark | C | El Puerto Anchoas | 26 | 05/18/2043 | Nanyang | CHN | Switch | Right | 6' 0" | 210 lbs | - |
| Sun, Pei | RP | El Puerto Anchoas | 29 | 12/02/2040 | Windsor | CAN | Right | Right | 6' 0" | 200 lbs | - |
| Suzuki, Joji | SP | Churuquita Grande Blackbirds | 31 | 03/11/2039 | Isesaki | JPN | Right | Right | 6' 4" | 200 lbs | - |
