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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saami, Nuruddin | 3B | Free Agent | 38 | 12/14/2031 | Durban | RSA | Right | Right | 6' 1" | 215 lbs | - |
| Salazar, Edinson | 1B | Erie Sea Wolves | 24 | 09/27/2045 | Farmington | USA | Right | Right | 6' 0" | 185 lbs | - |
| Salinas, Héctor | 1B | Santiago de Cuba Rough Riders | 27 | 06/05/2042 | Palo Negro | VEN | Right | Right | 6' 8" | 240 lbs | $350,000 |
| Samurakami, Hokichi | RP | Vancouver Ventures | 30 | 11/09/2039 | Osaka | JPN | Right | Right | 6' 4" | 215 lbs | $7,500,000 |
| Sánchez, Adrián | SS | Lagunillas Loros | 35 | 03/09/2035 | Havanna | CUB | Left | Right | 6' 1" | 200 lbs | $1,300,000 |
| Sánchez, Javy | RP | Vancouver Ventures | 23 | 08/27/2046 | San Pablo | USA | Switch | Right | 5' 10" | 170 lbs | - |
| Sánchez, Raúl | CF | Hamilton Steelers | 24 | 12/03/2045 | Villa de Cura | VEN | Switch | Right | 6' 2" | 200 lbs | $350,000 |
| Santana, Iván | C | Lagunillas Loros | 29 | 04/03/2041 | Mexicali | MEX | Right | Right | 6' 0" | 200 lbs | $350,000 |
| Sato, Ichiro | C | Maracaibo Jackals | 28 | 07/24/2041 | Goshogawara | JPN | Right | Right | 6' 1" | 200 lbs | $350,000 |
| Sato, Kenshin | RP | Maracaibo Jackals | 35 | 10/22/2034 | Higashimurayama | JPN | Left | Left | 5' 10" | 200 lbs | - |
| Sato, Mitsuzuka | RP | Maracaibo Jackals | 35 | 03/22/2035 | Tokyo | JPN | Left | Right | 6' 2" | 205 lbs | - |
| Scaduto, Emílio | CF | Valencia Cerveceros | 27 | 05/12/2042 | Santa Teresa | VEN | Right | Right | 6' 1" | 175 lbs | $5,200,000 |
| Sellers, Chris | 2B | Azua Tortugas | 27 | 07/11/2042 | Ardmore | USA | Right | Right | 6' 2" | 200 lbs | $3,750,000 |
| Serna, Raúl | 3B | Maracaibo Jackals | 30 | 02/03/2040 | Caracas | VEN | Right | Right | 6' 3" | 200 lbs | $960,000 |
| Sha, Kung-zheng | SP | Valencia Cerveceros | 26 | 08/17/2043 | Yancheng | CHN | Right | Right | 6' 0" | 195 lbs | $350,000 |
| Shibakusa, Motoyuki | RP | Maracaibo Jackals | 31 | 03/17/2039 | Yokohama | JPN | Left | Right | 5' 10" | 180 lbs | $350,000 |
| Shinoda, Matsuo | 2B | Lagunillas Loros | 27 | 04/19/2042 | Ueda | JPN | Left | Right | 6' 4" | 195 lbs | $2,000,000 |
| Shui, Bang-xao | 3B | Maracaibo Jackals | 25 | 06/04/2044 | Chongqing | CHN | Right | Right | 5' 9" | 185 lbs | $350,000 |
| Sim, Yong-chul | 3B | Maracaibo Jackals | 23 | 05/16/2046 | Seoul | KOR | Right | Right | 6' 0" | 200 lbs | - |
| Simpelo, Aurelio | RP | Vancouver Ventures | 32 | 11/29/2037 | Cienfuegos | CUB | Right | Right | 6' 7" | 240 lbs | $2,000,000 |
| Siu, Lien-ying | 3B | Erie Sea Wolves | 25 | 09/02/2044 | Yantai | CHN | Right | Right | 5' 9" | 185 lbs | $350,000 |
| Smith, Costard | CF | Free Agent | 31 | 08/07/2038 | Ecatepec | MEX | Right | Right | 6' 2" | 200 lbs | - |
| Soberanis, Hernán | RP | Valencia Cerveceros | 28 | 12/31/2041 | Jocotitlan | MEX | Right | Left | 6' 3" | 200 lbs | $1,000,000 |
| Song, Jung-won | SS | Vancouver Ventures | 37 | 12/25/2032 | Songnam | KOR | Switch | Right | 6' 2" | 200 lbs | $3,400,000 |
| Sonu, Chi-hyeon | 3B | Free Agent | 39 | 12/31/2030 | Kwangju | KOR | Right | Right | 6' 2" | 210 lbs | - |
| Sorana, António | SP | Maracaibo Jackals | 27 | 07/11/2042 | Panama | PAN | Right | Right | 6' 2" | 200 lbs | $350,000 |
| Soto, Enrique | 2B | Erie Sea Wolves | 40 | 09/24/2029 | Atoyac | MEX | Right | Right | 6' 1" | 195 lbs | $11,000,000 |
| Staitie, Garrison | SS | Maracaibo Jackals | 29 | 11/27/2040 | Brandon | CAN | Right | Right | 6' 2" | 195 lbs | $6,860,000 |
| Starks, Chris | RP | Valencia Cerveceros | 23 | 07/17/2046 | Port Alberni | CAN | Left | Left | 5' 11" | 165 lbs | $350,000 |
| Strelioff, Kevin | LF | Lagunillas Loros | 24 | 10/12/2045 | Vancouver | CAN | Right | Right | 6' 2" | 200 lbs | $350,000 |
| Suárez, Martino | 3B | Erie Sea Wolves | 28 | 02/22/2042 | Johnstown | USA | Right | Right | 6' 0" | 195 lbs | $450,000 |
| Suárez, Salvador | CF | Lagunillas Loros | 28 | 02/15/2042 | Upata | VEN | Right | Right | 6' 4" | 200 lbs | $493,500 |
| Sui, Shi-fa | C | Azua Tortugas | 31 | 07/25/2038 | Shawinigan | CAN | Left | Right | 6' 2" | 200 lbs | $550,000 |
| Sweet, Johnny | LF | Free Agent | 32 | 03/23/2038 | Toronto | CAN | Right | Right | 6' 2" | 200 lbs | - |
